Is it mutter (in terms of muktza) to take a hair off your clothing (with your hands) on shabbos?
Thanks.
Answer:
Yes, this is permitted.
The reason for this is that a hair is something of no significance at all, and therefore there is no problem of removing it.
The Gemara writes a similar concept concerning carrying on Shabbos, namely that “nitzotzos ein bahen mamash” – and the same will apply to the rabbinic concept of muktzeh.
Best wishes.