If one travels regularly to Yerushalayim – would seeing Har Hamuchos from the main highway exempt a person from having to say the special Brocha when actually physically visiting Har HaMenuchos.
Yes. If one actually sees the beis kevaros frequently, even from afar, one would not recite the berachah. The berachah is only recited if the beis kevaros has not been seen for thirty days.
Sources: Orach Chaim 224:12; Aruch Hashulchan mentions that the blessing is recited even from afar.